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Tyson Uppercut (GIF)
Perhaps the most lethal punch in boxing history was Mike Tyson’s uppercut. Every fighter who stepped into the ring with Iron Mike during his prime did so with fear in their eyes, largely because they knew at anytime they could wake up in a hospital bed after getting tagged by one of his vicious uppercuts.
As for his opponent in the above gif, I’m not so sure he was able to wake up at all after getting his bell rung by Tyson’s right uppercut.