The Indianapolis Colts have had a slow start to the season due in large part to injuries on the offensive side of the ball, most notably on the o-line.  Now it seems the defense has taken a hit as well, as it has been reported by various media outlets that all-pro safety Bob Sanders will be out 4-6 weeks with a high ankle sprain. 

In the past when Bob Sanders has missed a significant amount of time the Colts have struggled on defense.  This year during the first two weeks the Colts have been less than stellar on "D" with Sanders in the lineup. 

For now Bob Sanders will be out 4-6 weeks; being the quarterback of the Colts defense his loss is significant.  The Indianapolis Colts will have to find a way to win games without their best defensive player or they will be in trouble.

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