Oddsmakers currently have the Patriots listed as 3-point favorites versus the 49ers, while the game’s total is sitting at 41.

The Patriots lost to Miami 38-13 as a 12.5-point favorite in Week 3. The combined score went OVER the posted over/under total (37).

Matt Cassel completed 19-of-31 passes for 131 yards with a touchdown and an interception for New England, while Wes Welker caught six passes for 55 yards.

The 49ers lost to New Orleans 31-17 as a 7-point underdog in Week 4. The combined score fell UNDER the posted over/under total (48.5).

J.T. O’Sullivan threw for 257 yards with a touchdown and two interceptions for San Francisco, while Arnaz Battle had seven catches for 120 yards.

 

Team records:
New England: 2-1 SU, 1-2 ATS
San Francisco: 2-2 SU, 2-2 ATS

New England most recently:
When playing in October are 10-0
When playing on grass are 6-4
After being outgained are 7-3
When playing outside the division are 9-1

San Francisco most recently:
When playing in October are 2-8
When playing on grass are 4-6
After being outgained are 0-10
When playing outside the division are 3-7

A few trends to consider:
New England is 5-0 SU in its last 5 games on the road
New England is 20-2 SU in its last 22 games
The total has gone UNDER in 5 of New England’s last 6 games
The total has gone UNDER in 4 of New England’s last 5 games when playing San Francisco
The total has gone UNDER in 5 of San Francisco’s last 6 games at home
The total has gone UNDER in 4 of San Francisco’s last 5 games
The total has gone UNDER in 4 of San Francisco’s last 5 games when playing New England
San Francisco is 6-2 SU in its last 8 games when playing New England

Next up:
New England at San Diego, Sunday, October 12
San Francisco home to Philadelphia, Sunday, October 12

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