
The weekend is here with a full slate of MLB games. Intense battles between division rivals continue, and the home run prop bets for today are up and running. Today’s list will feature veteran sluggers who are not new to crushing bombs. As predicted yesterday, Corey Seager went deep. Here’s a look at the top 5 hitters poised to hit a home run tonight.
Top 5 MLB Home Run Prop Bets For June 21
5) Manny Machado (+310)

On top of the list, San Diego Padres star Manny Machado is a favorite at +340 odds. Machado’s track record speaks for itself, and he’s always a candidate to go deep. The slugger has a dozen home runs already, and he’s been successful by delivering in clutch moments.
4) Freddie Freeman (+300)

Following Machado on today’s list is Dodgers World Series hero Freddie Freeman. The veteran remains one of the most consistent hitters in the league. Freeman has nine home runs this MLB season with fewer plate appearances.
3) Jazz Chisholm Jr. (+295)

Chisholm is easily one of the top hitters on the Yankees’ squad. Known for his aggressive approach and flair, Jazz Chisholm Jr. is always a candidate to go deep, especially when he gets into favorable counts. The third baseman is having a great MLB season in the Bronx, and he’s already hit 10 home runs.
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2) Kerry Carpenter (+250)

Carpenter is one of the hottest hitters on the Detroit Tigers squad. The slugger has 13 home runs, and he’s been incredible with his performance. Carpenter is doing better than several other veteran sluggers, and he’s having the best MLB season in 2025.
1) Juan Soto (+240)

Soto is one of the most feared hitters in the MLB. His ability to challenge any pitcher is well-known. The Mets star has been decent, and he’s on pace to crush 35 home runs. Soto already has 14 bombs this season. He’s No. 1 on the list to go deep against the Philadelphia Phillies. The Mets are ranked No. 2 in the week 11 MLB power rankings.
Remember that odds are subject to change for those placing MLB home run prop bets, and outcomes are never guaranteed.
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